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Aspiron™ Natural Koji Iron

Importance of Iron in the human diet

Iron is an essential mineral for energy metabolism, neurological development, connective tissue synthesis, hormone synthesis and antioxidant activity. It is present in all cells in the human body and has several vital functions, such as: carrying oxygen from the lungs to all the tissues, as a key component of the hemoglobin (in red blood cells) protein and storing oxygen in the myoglobin (muscle) and neuroglobin (brain) proteins to support systemic metabolism.

People with Iron Deficiency may experience

  • Fatigue
  • Soft nails
  • Chapped lips
  • Mood changes
  • Muscle weakness
  • Immune deficiency
  • Long-term cognitive, motor and behavioral deficits (particularly infants and children). 

Source: Aggett, P.T Iron in 10th Edition Present Knowledge in Nutrition. 2012. Edited by John W. Erdman Jr., Ian A Macdonald, and Steven H. Zeisel.

Iron deficiency can be the result of a variety of issues, including poor diet, loss of blood (injury, menstrual cycle, surgery, disease, etc.), the body being unable to efficiently absorb iron, or the body cannot make or destroy red blood cells normally. Pregnant and lactating women may also be at risk of iron deficiency.
Source: National Institutes of Health

Features and Benefits of Aspiron™ Natural Koji Iron

Aspiron™ Natural Koji Iron is a unique, natural source of koji iron derived from Aspergillus oryzae (Koji culture). To produce our dietary iron, we use a centuries-old fermentation process re-fashioned and scaled for the global health needs of the 21st century. Koji culture has been used to produce Miso, Soy Sauce and Sake for over 2000 years.

Aspiron™ Natural Koji Iron contains from 6 to 8% of elemental iron and not less than 90% of the iron is associated with the koji culture mycelia as shown by Scanning (SEM) and Transmision Electron Microscopy (TEM).
  
   
SEM TEM

Aspiron™ is a bioavailable source of iron

The results from a stable isotope study in humans conducted at Iowa State University by Dr. Manju Reddy showed that Aspiron 10 mg iron is as bioavailable as ferrous sulfate at the same dose.


The absorption (Log %) of Fe57 as FeSO4 and Fe58 as Aspiron™ Natural Koji Iron in humans is the same n=16. (P=0.0762).

Regulatory Status and Intellectual Property

  • Aspergillus oryzae (also known as Koji culture) is GRAS on the basis of experience in common use in food before 1958.
  • The Aspiron™ Natural Koji Mineral Technology complies with the Dietary Supplement and Health Education Act (DSHEA).
  • Patents for process and composition have been filed in various countries.